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目的探讨生长抑素联合奥美拉唑治疗上消化道出血的临床疗效,以期为临床治疗提供参考。方法 80例上消化道出血患者,随机分为对照组和观察组,各40例。对照组患者在常规治疗基础上静脉滴注奥美拉唑钠,观察组患者在对照组基础上加用生长抑素,比较两组患者的治疗效果、平均止血时间、住院时间以及再出血率、死亡率。结果观察组患者治疗的显效率和总有效率显著高于对照组(P<0.05);观察组患者用药后平均止血时间和住院时间均短于对照组,且再出血率低于对照组(P<0.05)。结论生长抑素联合奥美拉唑治疗上消化道出血疗效显著优于单用奥美拉唑,且患者再出血率明显降低,是治疗上消化道出血的良好方法 ,值得临床推广。
Objective To investigate the clinical efficacy of somatostatin combined with omeprazole in the treatment of upper gastrointestinal bleeding in order to provide a reference for clinical treatment. Methods 80 patients with upper gastrointestinal bleeding were randomly divided into control group and observation group, 40 cases each. The patients in the control group were given omeprazole sodium intravenously on the basis of conventional treatment. The patients in the observation group were given somatostatin on the basis of the control group. The treatment effect, mean hemostasis time, hospitalization time and rebleeding rate were compared between the two groups. mortality rate. Results The effective rate and total effective rate of observation group were significantly higher than that of control group (P <0.05). The mean hemostasis time and hospitalization time of observation group were shorter than those of control group, and the rate of rebleeding was lower than that of control group <0.05). Conclusion The combination of somatostatin and omeprazole is superior to omeprazole alone in the treatment of upper gastrointestinal hemorrhage, and the rate of rebleeding is significantly lower in patients with upper gastrointestinal bleeding. Therefore, it is worthy of clinical promotion.