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本文是以生化基础知识来介绍肝昏迷的发病原因及其防治原则。氨中毒学说临床证明凡能使血氨增高的因素(如胃肠道出血、高蛋白膳食或口服铵盐)可使肝硬化病人诱发肝昏迷;部分病人的脑部症状与血氨浓度有关;凡昏迷初期血氨超过200μg%者预后不良,故该学说认为血氨增高是肝昏迷的主要发病因素。一、正常血氨的来源: 1.肠道吸收——肠菌对蛋白
This article is based on the basic knowledge of biochemistry to introduce the causes of hepatic coma and its prevention and treatment principles. Ammonia poisoning clinical evidence that any factor that can make blood ammonia increased (such as gastrointestinal bleeding, high protein diet or oral ammonium salt) can induce hepatic cirrhosis patients with hepatic coma; some patients with brain ammonia and ammonia concentration related; Coma in the early blood ammonia more than 200μg% poor prognosis, so the doctrine that increased blood ammonia is the main pathogenesis of hepatic coma. First, the source of normal blood ammonia: 1. Intestinal absorption - Enterobacteriaceae protein