Investigation of L/D-threonine substituted L-serine octamer ions by mass spectrometry and infrared p

• 作 者: Juan Ren Yi-Yun Wang Ru-Xia Fenga Xiang-Lei Kong
• 机 构: The State Key Laboratory of Elemento-Organic Chemistry, Nankai University,Collaborative Innovation C
• 出 处: Chinese Chemical Letters
• 发表日期: 2017年03期
• 关键词: substituted threonine serine intermolecular substitution bonds dissociation spec

Threonine-substituted serine octamer ions were generated by electrospray ionization(ESI) and investigated by mass spectrometry and infrared photodissociation(IRPD) spectroscopy. IRPD spectra of[L-Ser_7+ L/D-Thr_1]H~+and [L-Ser_6+ L/D-Thr_2]H~+were obtained in the range of 2700–3600 cm~(-1). Chiral differentiation was achieved by comparing their IRPD spectra. The main difference located in the range of 3300–3500 cm~(-1). And the results indicate the substitution of L-Ser by D-Thr could weaken the intermolecular H-bonds and loosen the original structures of serine octamers.

Threonine-substituted serine octamer ions were generated by electrospray ionization (ESI) and investigated by mass spectrometry and infrared photodissociation (IRPD) spectroscopy. IRPD spectra of [L-Ser_7 + L / D- Thr_1] H ~ + [L-Ser_6 + L / D-Thr_2] H ~ + were obtained in the range of 2700-3600 cm -1. Chiral differentiation was achieved by comparing their IRPD spectra. The main difference located in the range of 3300-3500 cm -1 . And the results indicate the substitution of L-Ser by D-Thr could weaken the intermolecular H-bonds and loosen the original structures of serine octamers.