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目的对拟行肺癌根治术的低肺功能患者进行常规肺功能检测和脉冲强迫振荡技术 (IOS)检测,评价术前肺功能参数预测低肺功能患者肺癌根治术后并发呼吸衰竭的价值。方法按照常规肺功能评价标准和术前肺功能测定结果,选择52例拟行肺癌根治术、低肺功能患者,根据术后是否发生呼吸衰竭分为呼衰组和非呼衰组。术前检测常规肺功能参数:第1秒用力呼气容积(FEV1．0)、肺活量(VC)及最大通气量(MVV);IOS检测参数:周边气道阻力(R5-R20)、弹性阻力(X5)、共振频律 (Fres)。结果两组FEV1．0、R5-R20、X5、Fres差异有统计学意义(P<0．05);Logistic回归分析显示仅 Fres为预测术后呼吸衰竭发生的独立因素(P<0．01)。结论 Fres有助于预测低肺功能肺癌患者全肺切除术后是否发生呼吸衰竭。
Objective To evaluate routine pulmonary function and pulsed forced oscillation technique (IOS) in patients with lung function undergoing radical resection of lung cancer. To evaluate the value of preoperative pulmonary function parameters in predicting respiratory failure in patients with low lung function after radical lung cancer surgery. Methods According to the standard lung function evaluation criteria and the results of preoperative pulmonary function tests, 52 patients with lung cancer undergoing radical mastectomy and low lung function were selected and classified as either respiratory failure group or non-respiratory failure group according to whether respiratory failure occurred after surgery. Preoperative detection of conventional lung function parameters: forced expiratory volume in 1 second (FEV1.0), vital capacity (VC), and maximal ventilation (MVV); IOS test parameters: peripheral airway resistance (R5-R20), elastic resistance ( X5) Resonance frequency law (Fres). Results There were significant differences in FEV1.0, R5-R20, X5 and Fres between the two groups (P<0.05). Logistic regression analysis showed that only Fres was an independent predictor of postoperative respiratory failure (P<0.01). . Conclusion Fres can help predict whether respiratory failure occurs after pneumonectomy in patients with low lung function lung cancer.