难治性癫痫患者颞叶切除的预后因素

• 作 者: Jeha L.E. Najm I.M. Bingaman W.E. 牛亚利
• 机 构: Dr.Department of Neurology S51,Cleveland Clinic Foundation,9500 Euclid Avenue,Cleveland,OH 44195,Uni
• 出 处: 世界核心医学期刊文摘(神经病学分册)
• 发表日期: 2006年12期
• 关键词: 难治性癫痫 前颞叶切除 抗癫痫药物 评估治疗 作外 抵抗性 短期 频率 个月

To assess short-and long-term seizure freedom,the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy.The mean follow-up duration was 5.5 years(range 1 to 14.1 years).Fifty-three percent of patients were seizure free at 10 years.The authors identified multiple predictors of recurrence.Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence,in addition to breakthrough seizures with discontinuation of antiepileptic drugs.

To assess short-and long-term seizure freedom, the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy. The mean follow-up duration was 5.5 years (range 1 to 14.1 years) .Fifty-three percent of patients were The authors identified multiple predictors of recurrence. Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence, in addition to breakthrough seizures with discontinuation of antiepileptic drugs.