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唾液聚糖(Sialoglycan)在排卵后2～3天出现于子宫内膜腺细胞内并在LH峰后6～7天分泌量最多。提示它的产生可能依赖于黄体酮,此物质可被单克隆抗体D_9B_1识别,因此可用免疫细胞化学方法检测。RU486是孕激素受体阻断剂,可以阻断激素对子宫内膜的支持作用。本文目的是观察抗孕酮药RU486对分泌期宫内膜分泌聚糖(glycan)的影响。对象为健康育龄妇女,经产妇,月经周期25～35天,无子宫内膜疾患,3个月未用过激素或宫内节育器,从滤泡期每天用放免法和酶免法分别测血和晨尿中LH,以便准确计算宫内膜活检日期。在LH峰后2～6天(LH+2～+6)行宫内膜活检作为基础i活检。对照组共44例,平
Sialoglycan appears in the endometrial glands 2 to 3 days after ovulation and secretes most 6 to 7 days after the LH peak. Suggesting that its production may depend on progesterone, this substance can be recognized by the monoclonal antibody D_9B_1, it can be detected by immunocytochemistry. RU486 is a progestin receptor blocker that blocks the hormone’s support of the endometrium. The purpose of this article is to investigate the effects of anti-progesterone RU486 on glycan secretion in the secretory endometrium. Subjects of healthy women of childbearing age, the mothers, the menstrual cycle 25 to 35 days, no endometrial disease, 3 months without hormones or intrauterine device, from the follicular phase by radioimmunoassay and enzyme immunoassay were measured blood And morning urine LH, in order to accurately calculate the endometrial biopsy date. Endometrial biopsy was performed on the basis of 2 to 6 days after LH peak (LH + 2 to + 6) biopsy. Control group, a total of 44 cases, flat