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目的探讨脑梗死患者的血小板四项参数的变化及临床意义。方法选取82例脑梗死住院患者和60例中老年健康体检者,分别测定血小板数(PLT)、血小板平均容积(MPV)、血小板分布宽度(PDW)及血小板压积(PCT),对血小板四项参数进行比较并做相关分析。结果脑梗死组PLT、PCT明显减少(P<0.05),MPV、PDW显著增高,与对照组比较差异有统计学意义(P<0.01)。恢复期与健康对照组比较差异无统计学意义。结论血小板参数的改变及血小板功能亢进是脑梗死发生的危险因素,动态观察血小板参数的变化对脑梗死的治疗及预后评估有一定的临床意义。
Objective To investigate the changes and clinical significance of four parameters of platelets in patients with cerebral infarction. Methods Eighty-two inpatients with cerebral infarction and 60 middle-aged and elderly healthy volunteers were enrolled in this study. PLT, MPV, PDW and PCT were measured, Parameters are compared and do correlation analysis. Results The levels of PLT and PCT in cerebral infarction group were significantly decreased (P <0.05), MPV and PDW were significantly higher than those in control group (P <0.01). There was no significant difference between convalescent group and healthy control group. Conclusion The changes of platelet parameters and platelet function are the risk factors of cerebral infarction. Dynamic observation of the changes of platelet parameters has certain clinical significance for the treatment and prognosis evaluation of cerebral infarction.