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目的:探讨非布司他联合中药治疗高尿酸症致慢性痛风的临床效果。方法:选取2013年2月-2014年2月来我院治疗的44例慢性痛风患者为研究依据,随机将其分为两组。观察组和对照组各22例,对照组患者行常规治疗措施,每日给予300mg的别嘌呤醇进行治疗,观察组基于常规治疗基础上采用非布司他药物治疗,每日的剂量控制为40mg,两组均治疗6个月,观察观察组与对照组临床疗效。结果:观察组血清尿酸水平为5mg/dl并趋于稳定状态,对照组的血清尿酸水平为9mg/dl,且观察组(95.45%)治疗总有效率明显高于对照组(50.09%),组间比较差异明显(P<0.05)。结论:高尿酸症致慢性痛风患者给予非布司他联合中药治疗,具有安全性高、疗效好的优点,值得在临床上推广应用。
Objective: To investigate the clinical efficacy of febuxostat combined with traditional Chinese medicine in the treatment of chronic gout induced by hyperuricemia. Methods: A total of 44 patients with chronic gout treated in our hospital from February 2013 to February 2014 were selected as the research basis and randomly divided into two groups. The observation group and the control group, 22 cases in each group, the control group patients underwent routine treatment, daily administration of 300mg of allopurinol treatment group based on conventional treatment with non-brevastatin medication, daily dose control 40mg , Both groups were treated for 6 months to observe the clinical efficacy of observation group and control group. Results: The serum uric acid level in the observation group was 5 mg / dl and stabilized. The serum uric acid level in the control group was 9 mg / dl, and the total effective rate in the observation group (95.45%) was significantly higher than that in the control group (50.09%). The difference was significant (P <0.05). Conclusion: Patients with chronic gout due to hyperuricemia are treated with febuxostat in combination with traditional Chinese medicine, which has the advantages of high safety and good curative effect, which is worth popularizing in clinic.