论文部分内容阅读
目的:研究在无排卵型月经失调的治疗中应用不同剂量的孕酮的实际疗效。方法:选取我院2015年2月-2016年4月收治的200例无排卵型月经失调患者进行分组研究,本组患者均行孕酮治疗,依据用药剂量的不同将其分别列入A(100mg)、B(200 mg)、C(300 mg)、D(400 mg)4组,每组各为50例,对比4组出血量、撤药性出血率、出血时间以及不良反应的发生率。结果:4组出血量、撤药性出血率、出血时间对比,差异均无统计学意义(P均>0.05);A、B、C、D 4组不良反应的发生率分别是4.0%、12.0%、24.0%、32.0%,差异均有统计学意义(P均<0.05)。结论:在无排卵型月经失调的治疗中,不同剂量(100-400mg)的孕酮均有着确切的疗效,但是低剂量孕酮的不良反应发生率明显较低,可推广。
Objective: To study the practical efficacy of different doses of progesterone in the treatment of anovulatory menstrual disorders. Methods: A total of 200 cases of anovulatory menopausal patients admitted to our hospital from February 2015 to April 2016 were divided into groups. All patients underwent progesterone treatment. The patients were enrolled in A (100mg ), B (200 mg), C (300 mg) and D (400 mg). Each group had 50 cases. The bleeding volume, withdrawal bleeding, bleeding time and incidence of adverse reactions were compared between the four groups. Results: There was no significant difference in bleeding volume, withdrawal bleeding rate and bleeding time between the four groups (all P> 0.05). The incidences of adverse reactions in groups A, B, C and D 4 were 4.0% and 12.0% , 24.0% and 32.0%, respectively (all P <0.05). CONCLUSION: In the treatment of anovulatory menstrual disorders, different dosage (100-400mg) of progesterone has the exact effect, but the incidence of adverse reactions of low dose progesterone is obviously lower, which can be promoted.