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目的 探讨乙肝病毒感染与胆泥、胆石形成的关系。 方法 收集35 例乙肝病毒感染患者和33 例非乙肝病毒感染患者的胆囊内胆汁,用偏振光显微镜进行检测。 结果 5 例乙肝病毒感染和4 例非乙肝病毒感染胆石症患者的胆汁均发现有胆泥形成(100 % ) 。30 例乙肝病毒感染患者的胆汁发现胆泥形成10 例(33 % ) ,其中8 例慢性肝炎患者的胆汁胆泥形成4 例(50 % ) ,29 例非乙肝病毒感染对照组患者发现胆泥3 例(10 % ) 。乙肝病毒感染组胆泥形成阳性检出率较对照组有显著差异( P< 001) 。 结论 胆泥形成是胆石形成的必经阶段,乙肝病毒感染与胆泥形成、胆石症发病率增高有密切关系。
Objective To investigate the relationship between hepatitis B virus infection and gallbladder and gallstone formation. Methods Gallbladder gallbladder was collected from 35 cases of hepatitis B virus infection and 33 cases of non-HBV infection and detected by polarized light microscope. Results Biliary formation was found in 5 cases of hepatitis B virus infection and in 4 cases of cholelithiasis patients without hepatitis B virus infection (100%). Cholesterol formation was found in 10 (33%) cases of bile in 30 patients with hepatitis B virus infection, of which 8 (48%) were found in 8 patients with chronic hepatitis and 29 in non-hepatitis B virus infection control group Example (10%). Hepatitis B virus infection bile formation positive rate was significantly different from the control group (P <0 01). Conclusion Bile formation is the necessary stage of gallstone formation. Hepatitis B virus infection is closely related to the formation of bile sludge and the increased incidence of cholelithiasis.