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目的探讨重度子痫前期合并胎儿生长受限经羊膜腔灌注治疗后的妊娠结局。方法分析1997年1月至2010年10月在我院系统产检、分娩的重度子痫前期合并胎儿生长受限的孕妇共40例,予羊膜腔内灌注小儿复方氨基酸100ml(A组),同期抽取重度子痫前期合并胎儿生长受限的孕产妇36例(B组)。并对两组的妊娠结局及围生儿预后进行对比分析。结果重度子痫前期合并胎儿生长受限治疗组(A组)新生儿窒息、早产、新生儿呼吸窘迫综合征、新生儿肺炎,高胆红素血症、低出生体重儿的发生率显著降低。结论重度子痫前期合并胎儿生长受限是一种严重危害围生儿的疾病,积极的处理有助于改善围生儿的预后。
Objective To investigate the pregnancy outcome of severe preeclampsia with fetal growth restriction and amniotic cavity perfusion. Methods A total of 40 pregnant women with severe preeclampsia and fetal growth restriction in our hospital from January 1997 to October 2010 were enrolled in this study. A total of 40 infants were infused with 100ml of compound amino acids (A group) Thirty-six pregnant women with severe preeclampsia and limited fetal growth (group B). The pregnancy outcomes and perinatal outcome were compared between the two groups. Results The incidence of neonatal asphyxia, premature birth, neonatal respiratory distress syndrome, neonatal pneumonia, hyperbilirubinemia and low birth weight children was significantly decreased in severe preeclampsia with fetal growth restriction group (group A). Conclusion Severe preeclampsia combined with fetal growth restriction is a serious risk of perinatal disease, and positive treatment can help to improve the prognosis of perinatal children.