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目的阐明血液粘度与心输出量存在着规律性的联系。方法在20例正常人及82例心脏病患者中,以锥板法测定不同切变率的全血粘度(加)、血浆粘度(仰),以二维超声心动图按改良Simpsom氏法测定心输出量(CO),所得数据进行直线相关回归分析。结果CO与Db、op均呈显著负相关。进一步将病例分组对照,以比较降低血粘度(甲组巾扩张阻力血管(乙组)两者对CO的影响:甲组静滴低分子右旋糖面300ml加唤蛇抗栓酶 1. su和口服抵克力得(Ticlid) 500mg,每天卫次,用药两周;乙组静滴酚妥拉明(Regitime)20mg,每天 1次,用药两周。两组病例各在用药前及停药手1~5周每周测定一次CO,5次的CO均数作为该组治疗的平均心输出量水平。经对照检验:甲组在提高心输出量水平上有更明显的作用。结论血液粘度是影响心输出量比较稳定的因素,降粘治疗对增加心输出量是有效、平稳、持久的疗法。
Objective To elucidate the relationship between blood viscosity and cardiac output. Methods In 20 normal subjects and 82 patients with heart disease, the whole blood viscosity (plus) and plasma viscosity (supine) with different shear rates were determined by cone plate method. The heart was measured by modified Simpsom’s method with two-dimensional echocardiography Output (CO), the resulting data linear regression analysis. Results CO and Db, op showed a significant negative correlation. The patients were further grouped and compared to lower the blood viscosity (Group A towel dilation resistance blood vessels (Group B) on both CO: intravenous infusion of low molecular weight dextrose face 300ml plus call snake antithrombin 1. su and Oral Ticlide 500mg, daily Wei times, medication for two weeks; B intravenous infusion of phentolamine (Regitime) 20mg, 1 day, medication for two weeks .Two groups of patients before treatment and withdrawal 1 to 5 weeks a CO, 5 times a week as the mean CO output of the group treatment of the average cardiac output.Control test: A group to improve cardiac output levels have a more significant effect.Conclusion The blood viscosity is Factors that affect the stability of cardiac output, viscosity-reducing therapy to increase cardiac output is an effective, stable, long-lasting therapy.