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检测我国７个地区３６９株ＥＴＥＣ的热敏肠毒素（ＬＴ）、人源性耐热肠毒素（ＳＴｈ）、猪源性耐热肠毒素（ＳＴｐ）以及ＥＴＥＣ两种主要的定居因子ＣＦＡⅠ和ＣＦＡⅡ。结果表明：我国ＥＴＥＣ毒力型以ＳＴ为最常见，其中又以单一ＳＴｐ多见，其次为单一ＳＴｈ；ＬＴ毒力型主要见于南方。首次阐明了我国部分地区ＥＴＥＣ菌株ＣＦＡⅠ和ＣＦＡⅡ的分布特点：各地ＣＦＡⅠ和ＣＦＡⅡ的总检出率为３３．３％～５４．６％，平均５０．８％；ＣＦＡⅠ和ＣＦＡⅡ均多见于ＳＴｐ阳性的菌株，与一般报道相似；但我们发现：ＣＦＡⅠ和ＣＦＡⅡ在单一ＬＴ阳性的菌株中也有较高的阳性率；ＣＦＡⅡ较ＣＦＡⅠ常见，ＣＦＡⅠ则主要见于南方地区；病人、健康人和环境株的毒素型相近，ＣＦＡⅠ和ＣＦＡⅡ则病人株显著高于其它来源菌株，提示这两类定居因子在ＥＴＥＣ致病中的重要性
Totally 369 ETEC strains of heat-labile enterotoxin (LT), human-derived heat-stable enterotoxin (STh), porcine heat-stable enterotoxin (STp) and two major settlement factors CFAⅠand CFAⅡwere detected. The results showed that ST was the most common type of ETEC virulence in China, with single STp being more common and followed by single STh. LT virulence was mainly found in the south. The distribution characteristics of CFAⅠ and CFAⅡof ETEC strains in some areas of China were elucidated for the first time. The overall detection rates of CFAⅠ and CFAⅡ were 33.3% ~ 54.6%, with an average of 50.8%. CFAⅠ and CFAⅡ were more common in STp-positive However, we found that CFAⅠand CFAⅡhave higher positive rates in single LT positive strains, CFAⅡis more common than CFAⅠand CFAⅠis mainly found in the southern part of China. The virulence of patients, healthy individuals and environmental strains Similar, CFA Ⅰ and CFA Ⅱ patient strains were significantly higher than other strains, suggesting that these two types of settlement factor in the pathogenesis of ETEC importance