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目的 调查2014年克拉玛依市中心医院(简称克市中心医院)慢性阻塞性肺疾病(COPD)住院患者的费用和用药等情况,为开展COPD循证药学工作提供依据和参考.方法 提取克市中心医院信息管理系统2014年出院病历中第一诊断为COPD或慢性阻塞性肺病伴急性加重(AECOPD)患者的费用、用药等资料,采用Excel 2007软件对频数、构成比和累积构成比等指标进行统计分析.结果 2014年克市中心医院COPD/AECOPD住院患者共194例,平均年龄为74.28±7.81岁.共用药53种,用药总频次1 798人次,人均费用7 419.78元.使用频次前三位的药物是布地奈德混悬液、孟鲁司特片、甲泼尼龙针.人均费用前三位的药物是哌拉西林他唑巴坦、亚胺培南西司他丁钠、莫西沙星注射剂.结论 克拉玛依市中心医院2014年COPD/AECOPD住院患者治疗用药以布地奈德混悬液、孟鲁司特片和甲泼尼龙针为主;人均费用前三位为哌拉西林他唑巴坦、亚胺培南西司他丁钠和莫西沙星注射剂.“,”Objective To investigate drug usage and costs of chronic obstructive pulmonary disease (COPD) inpatients in Karamay Central Hospital in 2014 and to provide evidence and reference for evidence-based pharmacy study on COPD.Methods The information of drug use and expenditure of COPD inpatients were collected from the hospital information system (HIS).We analyzed the data including frequency,proportion and cumulative proportion by Excel 2007 software.Results A total of 194 inpatients with COPD/AECOPD were included in Karamay Central Hospital in 2014,the average age was 74.28±7.81 years old.Fifty-three drugs were used for COPD treatment;the total frequency were 1 798 times and per capita cost was 7 419.78 yuan.The top three used drugs were budesonide suspension,montelukast tablets and methylprednisolone injection.In total expenditure,the cost of piperacillin-tazobactam,imipenem/cilastatin and moxifloxacin injection ranked top three.Conclusion The top 3 used drugs are budesonide suspension,montelukast tablets and methylprednisolone injection for COPD inpatients in Karamay Central Hospital in 2014,while the top 3 total expenditure drugs are piperacillin-tazobactam,imipenem/cilastatin and moxifloxacin injection.