Tuning the optical properties of BODIPY dye through Cu(I) catalyzed azide-alkyne cycloaddition(CuAAC

• 作 者: SUTHIWANGCHAROEN Nisaraporn
• 机 构: Department of Chemistry and Biochemistry,University of South Carolina,Columbia,SC 29208,USA,
• 出 处: 中国科学:化学
• 发表日期: 2012年02期
• 关键词: azide catalyzed CuAAC reaction switched reacting carries chloroform sequential F

Borondipyrromethenes(BODIPY) are a class of fluorescent dyes whose fluorescence quantum yields are generally high and independent of the solvent.In this paper,we report the synthesis of a new type of BODIPY compound that carries an azido group on the 3-position of the pyrrole core.The azido group quenches the fluorescence of the dye due to its weak electron-donating effect.The fluorescence of the BODIPY dye can be switched on after reacting with alkynes via a Cu(I) catalyzed azide-alkyne cycloaddition(CuAAC) reaction.We further demonstrate that this azido-BODIPY compound can be used in the cell imaging applications.

In a paper of the new type of BODIPY compound that carries an azido group on the 3-position of the pyrrole core. The azido group quenches the fluorescence of the dye due to its weak electron-donating effect. The fluorescence of the BODIPY dye can be switched on after reacting with alkynes via a Cu (I) catalyzed azide-alkyne cycloaddition (CuAAC) reaction .We further demonstrate that this azido-BODIPY compound can be used in the cell imaging applications.