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目的:探讨急性有机磷农药中毒并呼吸衰竭急诊抢救。方法:本次研究选择的对象共30例,均为我院2010年3月至2013年2月收治的急性有机磷农药中毒并发呼吸衰竭的患者,均采用急诊机械通气治疗,回顾临床资料。结果:本组30例患者中,成功抢救27例,占90%;放弃治疗2例,占6.7%;死于多器官功能衰竭综合征1例,占3.3%。机械通气后PaO2指标及SpO2指标与通气前比较明显改善,差异有统计学意义(P<0.05)。均无机械通气相关并发症发生。结论:急性有机磷农药中毒合并呼吸衰竭发生的患者,需加强急诊救治,积极行机械通气治疗,可提高抢救成功率,降低死亡率,改善预后,具有非常积极的临床意义。
Objective: To investigate acute organophosphorus pesticide poisoning and emergency treatment of respiratory failure. Methods: A total of 30 subjects were selected in this study. All of them were patients with acute organophosphorus pesticide poisoning complicated with respiratory failure from March 2010 to February 2013 in our hospital. All patients were treated with emergency mechanical ventilation and the clinical data were reviewed. Results: Among the 30 patients in this group, 27 cases were rescued successfully, accounting for 90%; 2 cases were given up for treatment, accounting for 6.7%; 1 died of multiple organ failure syndrome, accounting for 3.3%. PaO2 index and SpO2 index after mechanical ventilation were significantly improved compared with those before ventilation, the difference was statistically significant (P <0.05). No mechanical ventilation related complications occurred. Conclusion: Patients with acute organophosphorus pesticide poisoning and respiratory failure need to strengthen emergency treatment and active mechanical ventilation, which can improve the success rate of rescue, reduce mortality and improve prognosis. It has a very positive clinical significance.