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本文应用弓形虫不同毒力虫株感染同一种宿主和应用同一毒力虫株感染不同动物及不同免疫状态的动物宿主，观察了ｓｔｄ／ｄｄｙ小鼠和长爪沙鼠对ＲＨ株、ＢＥＶ株和ＦＵＫ株弓形虫的易感性．结果见到，弱毒株（ＢＥＶ株－小鼠）和无毒株（ＦＵＫ株－小鼠）对长爪沙鼠具有强致死性．提出虫株毒力除了与原虫自身的生物学特性有关外，也是寄生虫－宿主相互作用的综合表现．因此，在根据实验动物的临床指标评价虫株毒力时，需附加动物模型条件.
In this paper, Toxoplasma gondii different strains of virulent strains infected with the same host and the same virulent strains infected with different animals and different immune status of the animal host, std / ddy mice and gerbils RH strain, BEV strain and FUK Strain Toxoplasma gondii susceptibility. As a result, it was found that the attenuated strain (BEV strain - mouse) and the avirulent strain (FUK strain - mouse) were highly lethal to Meriones unguiculatus. In addition to the virulence of the protozoa, it was suggested that the virulence of the strain was also related to the parasite-host interaction. Therefore, animal model conditions need to be added when evaluating the virulence of the strain according to the clinical indicators of experimental animals.