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脂质过氧化损伤和前列腺素代谢失衡可能与冠心病的发生与发展关系密切。我们对保健干部中的老年冠心病及对照组各40例测定了血清脂质过氧化物(LPO)、超氧化物歧化酶(SOD)水平,血栓素 A_2(TXA_2)及前列环素(PGI_2)的代谢产物血栓素 B_2(TXB_2)及6-酮-前列腺索 F_(1α)(6-酮-PGF_(1α))的含量,经对照分析探讨其关系。
Lipid peroxidation injury and prostaglandin metabolism imbalance may be closely related to the occurrence and development of coronary heart disease. We measured serum levels of lipid peroxidation (LPO), superoxide dismutase (SOD), TXA_2 and PGI_2 in 40 elderly patients with coronary heart disease and control group, (TXB_2) and 6-keto-PGF 1α (6-keto-PGF_ (1α)) were detected by flow cytometry.