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继证实克矽平对实验性矽肺具有明显疗效之后,在筛选中又发现亚胺—胺类高分子聚合物“津5”也有一定疗效.在缺乏治疗矽肺有效药物的情况下,对这一新化合物有必要进一步研究。现将我们在不同种属动物身上观察到的亚胺—胺类聚合物“津5”对实验性矽肺的疗效和毒性报告如下:
Following the confirmation of Ke Yiping’s significant effect on experimental silicosis, the imine-amine polymer “Zi 5” was also found to have a certain effect in the screening. In the absence of effective drugs for the treatment of silyphosis, this new Compounds need further study. The efficacy and toxicity of the imine-amine polymer “Zi 5” that we observed in different species of animals on experimental silicosis are reported as follows: