论文部分内容阅读
目的:探讨炎性乳腺癌的临床特点、治疗经验及预后因素。方法:对我院1987~2002年收治的48例炎性乳腺癌的临床资料进行回顾性分析,按TNM分期,Ⅲb期37例,Ⅳ期11例,无特定的组织学类型, 48例患者均接受综合治疗。结果:全组平均生存期34个月, 2年生存率46.9%, 5年生存率34.4%,Ⅲb期生存5年者11例,Ⅲb期1年内死亡者有7例,Ⅳ期中3例1年内死亡。结论:炎性乳腺癌恶性程度高,预后极差。其乳房皮肤红斑范围、术前对化疗药物的敏感性、腋窝淋巴结转移状况和局部血管受累情况以及分期等与预后有关,主张采用新辅助化疗手术或局部放疗辅助化疗的综合方法进行治疗。
Objective: To investigate the clinical features, treatment experience and prognostic factors of inflammatory breast cancer. Methods: The clinical data of 48 cases of inflammatory breast cancer admitted from 1987 to 2002 in our hospital were retrospectively analyzed. According to TNM stage, 37 cases were in stage Ⅲb and 11 cases were in stage Ⅳ. There were no specific histological types and 48 cases were Accept comprehensive treatment. Results: The mean survival time was 34 months, the 2-year survival rate was 46.9%, the 5-year survival rate was 34.4%, 11 cases survived 5 years in stage Ⅲb, 7 cases died in 1 year in stage Ⅲb, 3 cases in stage Ⅳ were within 1 year death. Conclusion: Inflammatory breast cancer is highly malignant with poor prognosis. The range of breast skin erythema, preoperative sensitivity to chemotherapy drugs, axillary lymph node metastasis and local vascular involvement and staging and prognosis, advocated the use of neoadjuvant chemotherapy or local radiotherapy adjuvant chemotherapy for treatment.