论文部分内容阅读
对86例慢阻肺和肺心病急性期患者用放射免疫分析法测定血浆肾素活性、血管紧张素Ⅱ、醛固酮及促肾上腺皮质激素含量。发现患者上述各项指标均较正常人明显升高(P<0.01);同时还发现严重低氧血症和伴高碳酸血症者(PaO_2平均5.33kPa、PaCO_2平均9.46kPa)肾素活性、血管紧张素Ⅱ、醛固酮的含量上升则相当显著,提示肾素-血管紧张素-醛固酮系统的活性与PaO_2、PaCO_2密切相关。
Plasma levels of renin, angiotensin Ⅱ, aldosterone and adrenocorticotropic hormone were measured by radioimmunoassay in 86 chronic obstructive pulmonary disease and pulmonary heart disease patients. Found that the above indicators were significantly higher than the normal (P <0.01); also found severe hypoxemia and associated with hypercapnia (PaO 2 average 5.33kPa, PaCO 2 average 9.46kPa) renin activity, blood vessels Tensin II, aldosterone content was quite significant, suggesting that the activity of renin - angiotensin - aldosterone system and PaO_2, PaCO_2 are closely related.