论文部分内容阅读
目的：观察国产与进口２种硝酸异山梨酯注射液治疗冠心病心绞痛的疗效。方法：将冠心病心绞痛病人７０例随机分为２组，试验组３５例（男性２１例，女性１４例；年龄５８±ｓ７ａ）用国产硝酸异山梨酯注射液治疗。对照组３５例（男性２７例，女性８例；年龄５８±８ａ）用进口硝酸异山梨酯注射液治疗。２组用药方法均为５０ｍｇ加入５％葡萄糖注射液５００ｍＬ中静脉滴注，ｑｄ，疗程均为１０ｄ。结果：对心绞痛的治疗效果，２组总有效率均为１００％，显效率分别为６６％和６９％；对缺血性心电图表现的疗效，２组总有效率分别为７４％和７７％，显效率分别为２０％和２３％（Ｐ＞０．０５）。不良反应率分别为１４％和１２％。结论：国产与进口硝酸异山梨酯注射液治疗冠心病心绞痛疗效无显著差异。
Objective: To observe the effect of domestic and imported isosorbide dinitrate injection on angina pectoris of coronary heart disease. Methods: Seventy patients with coronary heart disease and angina pectoris were randomly divided into two groups. 35 patients (21 males and 14 females; age 58 ± s7a) were treated with domestic isosorbide dinitrate injection. Control group 35 patients (27 males and 8 females; age 58 ± 8a) were treated with isosorbide dinitrate injection. 2 groups were treated with 50mg 5% glucose injection 500mL intravenous infusion, qd, treatment were 10d. Results: For the treatment of angina pectoris, the total effective rates of two groups were 100%, the effective rates were 66% and 69% respectively. The effective rates of ischemic electrocardiogram were 74% and 77% Significantly effective rates were 20% and 23% (P> 0.05). Adverse reaction rates were 14% and 12%, respectively. Conclusion: Domestic and imported isosorbide dinitrate injection for the treatment of angina pectoris no significant difference.