论文部分内容阅读
目的 探讨参麦注射液对恶性肿瘤化疗增效减毒作用。方法 采用参麦注射液配合化疗与单用化疗对照治疗恶性肿瘤病人 10 8例 ,并对疗效、免疫功能及毒副作用进行评价。结果 参麦注射液治疗组有效率 (56 4 5% )高于对照组 (39 13% ) ,以胃癌明显 ;参麦注射液治疗组口腔溃疡及静脉炎的发生率明显低于对照组 (P <0 0 5或 0 0 1) ,而且对照组白细胞明显下降 ,治疗组不明显 ;参麦注射液治疗组治疗后NK细胞数、CD4 及CD4 CD8值升高 ,CD8下降 (P <0 0 5或 0 0 1) ,而对照组变化不明显 (P >0 0 5) ,两组体液免疫指标治疗前后变化不明显。结论 参麦注射液对恶性肿瘤化疗有增效、减毒作用 ,且能提高细胞免疫功能 ,值得临床推广应用。
Objective To investigate the effect of Shenmai injection on synergistic and attenuated chemotherapy for malignant tumors. Methods A total of 108 patients with malignant tumors were treated with Shenmai injection combined with chemotherapy and chemotherapy alone. The efficacy, immune function and side effects were evaluated. Results The effective rate of Shenmai injection was (56 4 5%) higher than that of the control group (39 13%), with significant gastric cancer; the incidence of oral ulcers and phlebitis was significantly lower in the Shenmai injection treatment group than in the control group (P <0 0 5 or 0 0 1), and the control group, white blood cells decreased significantly, the treatment group was not obvious; Shenmai injection treatment group NK cell count, CD4 and CD4 CD8 values increased, CD8 decreased (P <0 0 5 Or 0 0 1), but the control group did not change significantly (P > 0 05), two groups of humoral immune indicators before and after treatment did not change significantly. Conclusion Shenmai injection has a synergistic and attenuating effect on the chemotherapy of malignant tumors, and can improve the cellular immune function. It is worthy of clinical application.