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目的探讨营养方式的选择对重症急性胰腺炎(SAP)预后的影响。方法选择接受营养治疗的SAP患者154例,其中78例接受全肠外营养(TPN);76例同时接受肠外营养(PN)和肠内营养(EN)。比较两组患者感染率、并发症发生率、住院时间和死亡率的差异。结果与TPN组相比,PN+EN组患者的胰腺感染率PN+EN 7.8%,TPN12.8%,P<0.05,其他部位感染率PN+EN17.1%,TPN24.3%,P<0.05,并发症发生率(PN+EN 31.5%,TPN 38.4%,P<0.05)明显降低,住院时间[PN+EN(36.87±8.93)d,TPN(48.17±14.5)d]明显缩短,死亡率(11.8%,TPN 10.2%,P>0.05)两组无差异。结论PN和EN联合应用是SAP首选的营养方式。
Objective To investigate the effect of nutritional mode on the prognosis of severe acute pancreatitis (SAP). Methods A total of 154 patients with SAP were enrolled in this study. Totally 78 patients received total parenteral nutrition (TPN) and 76 patients received parenteral nutrition (PN) and enteral nutrition (EN) simultaneously. The infection rate, complication rate, length of hospital stay and mortality of the two groups were compared. Results Compared with TPN group, PN + EN group had PN + EN 7.8%, TPN12.8%, P <0.05, PN + EN17.1%, TPN24.3%, P <0.05 , The incidence of complications (PN + EN 31.5%, TPN 38.4%, P <0.05) decreased significantly, and the length of hospital stay [PN + EN (36.87 ± 8.93) d, TPN (48.17 ± 14.5) d] 11.8%, TPN 10.2%, P> 0.05) There was no difference between the two groups. Conclusion The combination of PN and EN is the SAP preferred nutrition.