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目的：探讨替罗非班在急性ST 段抬高型心肌梗死行急诊经皮冠状动脉介入治疗患者中的应用及护理干预效果。方法将160例急性S T段抬高型心肌梗死患者采用随机数字表法分为研究组和对照组各80例，两组急诊经皮冠状动脉介入治疗围手术期均给予常规抗血栓治疗及系统化护理干预，研究组在此基础上术前予以替罗非班治疗，比较两组术后T IM I血流分级情况、心血管事件及出血并发症发生率、术后ST段回落程度。结果术后研究组患者血流分级情况显著优于对照组（P＜0．01），住院期间心血管事件发生率显著低于对照组（P＜0．01），两组患者出血并发症发生率比较差异无显著性（ P＞0．05），术后30 m in研究组S T段下降≥50％的发生率显著高于对照组（P＜0．01），术后2 h两组比较差异无显著性。结论对急性ST 段抬高型心肌梗死行急诊经皮冠状动脉介入治疗患者联合替罗非班治疗及系统化护理干预，能有效改善患者的冠脉微循环灌注状态，降低术后心血管事件发生率，提高患者的治疗效果。“,”Objective To explore the effect of tirofiban applied in ST‐elevation myocardial infarction (STEMI) patients undergoing emergency percutaneous coronary intervention (PCI) .Methods A total of 160 acute STEMI patients were randomly assigned to research and control group of 80 ones each ,an‐tithrombotic therapies given to both groups in peroperative period of emergency PCI ,on this basis research group was plus preoperative tirofiban ,and postoperative intergroup TIMI blood flow classifications ,cadio‐vascular events ,bleeding complication incidences and ST segment resolutions compared .Results Postop‐erative blood flow classifications were significantly better (P< 0 .01) ,the incidences of cadiovascular e‐vents lower (P0 .05) ,patients with ST segment resolution ≥ 50% were more in research than in control group within 30 minutes after operation (P0 .05) .Conclusion Tirofiban could effectively im‐prove myocardial perfusion of STEMI patients undergoing emergency PCI ,reduce the incidence of postop‐erative cadiovascular events ,and boost treatment effectiveness .