论文部分内容阅读
目的：了解良性与恶性胰腺神经内分泌肿瘤的临床特征及C T征象。方法将80例胰腺神经内分泌肿瘤患者根据肿瘤性质分为两组，良性组37例，恶性组43例。比较两组的临床特征及CT征象。结果恶性组腹部包块及低血糖症检出率显著高于良性组（P＜0．05或0．01），无明显症状率显著低于良性组（P＜0．01）；囊变坏死程度、肿瘤形态、侵袭性、强化方式与良性组比较差异有显著性（P＜0．05或0．01），肿瘤直径及增强扫描动脉期、静脉期及平衡期CT值显著高于良性组（P＜0．05或0．01）。两组肿瘤部位、胰胆管扩张情况及平扫CT值比较差异无显著性（P＞0．05）。结论恶性胰腺神经内分泌肿瘤患者腹部包块及低血糖发生率高，具有瘤体直径较大、形态不规则，有囊变坏死、侵袭性高、不均匀强化等CT征象，综合其临床特征及CT征象表现，对判断肿瘤的性质具有重要意义。“,”Objective To survey the clinical features and CT signs of benign and malignant pancreatic neu‐roendocrineneoplasm (pNENs) .Methods Eight pNENs patients were assigned to benign (n=37) and malignant (n=43) according to tumor qualities .Intergroup clinical features and CT signs were compared . Results Detection rates of abdominal mass and hypoglycemia were significantly higher (P<0 .05 or 0 .01) and non‐overt symptom rate lower (P<0 .01) in malignant than in benign group ;there were significant group differences in cystic degeneration and necrosis degrees ,tumor morphology ,invasion and reinforce‐ment ways (P<0 .05 or 0 .01) ,tumor diameter and CT values of arterial ,venous and balancing phase of contrast enhancement were significantly larger in malignant than in benign group (P 0 .05) .Conclusion The incidences of abdominal mass and hypoglycemia are higher in pNENs patients ,tumor diameter is larger and morphology irregular ,they have such CT signs as cystic de‐generation and necrosis ,high invasion and asymmetrical enhancement ,and the combination of clinical fea‐tures and CT signs has an important significance for judging tumor quality .