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为探测典型先兆子痫和HELLP(溶血、肝酶升高和低血小板)综合征病人与正常血压孕妇之间肿瘤坏死因子(TNF)T2等位基因出现频率的差异,1990～1995年从住院分娩的病人中取血,其中131例先兆子痫,75例HELLP综合征和41例正常血压孕妇。先兆子痫病人均有持续高血压(>18.7/12.0kPa,>140/90mmHg),24h蛋白尿至少500mg,或反复半定量试验3+～4+。而且,病人均符合ACOG对严重先兆子痫的规定。孕妇的平均年龄25(15～39)岁,妊娠次数和分娩次数分别为2(1～8)和1(0～5)。分娩时的平均收缩压为22.7
To detect differences in the frequency of tumor necrosis factor (TNF) T2 alleles between patients with typical preeclampsia and HELLP (hemolysis, elevated liver enzymes and low platelet) syndrome and normotensive males, hospitalization was performed from 1990 to 1995 Of 131 patients with preeclampsia, 75 cases of HELLP syndrome and 41 cases of normotensive pregnant women. Patients with preeclampsia had persistent hypertension (> 18.7 / 12.0 kPa,> 140/90 mmHg), proteinuria for at least 500 mg for 24 hours or repeated cycles of 3 + to 4 +. Moreover, all patients met the ACOG guidelines for severe preeclampsia. The average age of pregnant women 25 (15 to 39) years old, the number of pregnancies and childbirth were 2 (1 ~ 8) and 1 (0 ~ 5). The average systolic blood pressure at delivery was 22.7