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我院最近在静注白霉素治疗一例支气管肺炎时发生过敏性休克,特报道如下: 患孩刘×,男性,年龄2个月,住院号91367 患孩因发热,咳嗽,气逼伴腹泻于一九七九年六月十九日入院。入院诊断:支气管肺炎、Ⅱ°营养不良。经用苯甲异恶唑青霉素,止咳合剂治疗八天,发热未退,肺部罗音未减。根据临床观察及血象检查,考虑为病毒性肺炎,遂停用苯甲异恶唑青霉素。改用酒石酸白霉素20万单位溶于4:1溶液10毫升中静脉注射,七分钟注完。注药后约10分钟,患儿面色苍白,口唇青紫,呼吸表浅,心音微弱,脉搏不能触及,皮肤湿润,四肢冷绀。考虑可能为白霉素过敏,立即皮下注射1%盐酸肾上腺素0.25毫升,给氧及头低卧位,约10分钟后,逐渐见病孩面色好转。唇色转红,呼吸渐平稳,心音渐有力,继而脉搏可触及。约2小时后全身情况恢复到注药前。随后改用鱼腥草注射,用药第六天,体温正常,肺部罗音消失,继续观察三天,痊愈出院。
Our hospital recently intravenous injection of white mold in the treatment of bronchial pneumonia, anaphylactic shock occurs, the special report is as follows: The child Liu ×, male, age 2 months, hospitalized 91367 children due to fever, cough, gas with diarrhea on She was admitted on June 19, 1979. Admission diagnosis: bronchial pneumonia, Ⅱ ° malnutrition. After using benzofenoxazole penicillin, cough mixture for eight days, fever did not retreat, pulmonary rales not reduced. According to clinical observations and blood tests, consider viral pneumonia, and then stop the use of isoxazole penicillin. Switch to 20 million units of leucine tartrate dissolved in 4: 1 solution of 10 ml intravenous injection, seven minutes note finished. About 10 minutes after injection, children pale, lips purple, superficial breathing, weak heart sounds, pulse can not touch, the skin moist, cyanotic limbs. Consider possible allergy to white mold, immediately subcutaneous injection of 1% 0.25% epinephrine hydrochloride, oxygen and head low lying position, about 10 minutes later, gradually see the sick child looking better. Lip color turn red, breathing steady, heart sound gradually powerful, then the pulse can be touched. About 2 hours after the general condition restored to injection. Then switch to Houttuynia injection, medication the sixth day, normal body temperature, pulmonary rales disappeared, continue to observe the three days, discharged.