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1984年,我国从引起食物中毒的变质甘蔗中分离到了一种产毒霉菌一一节菱孢(Arthrinium),并证明节菱孢是变质甘蔗中毒的病原菌,它的有毒代谢产物3-硝基丙酸是引起中毒的主要致病毒素。从而,阐明了这种十多年来一直原因不明的食物中毒的病因。 3-硝基丙酸(BNPA)是一种由某些高等植物和真菌产生的有毒物质。早在1920年Gorter从狗角藤属植物(Hiptage mandablota Gaertn)的茎皮中提取到一种葡萄糖苷——狗角藤苷(hiptagin),经水解后得到一种酸,命名为狗角藤酸(hiptagenic acid)。1949年,Carter等证明了这种物质为BNPA。并在以后相继从多种高等植物和真菌的代谢产物中分离到。60多年来,国外科学家对BNPA的理
In 1984, China produced a strain of Arthrinium that produces poisonous mold from sugarcane that causes food poisoning, and proved that Spodoptera frugiperda is the pathogen of metamorphic sugarcane poisoning. Its toxic metabolite 3-nitropropane Acid is the major causative agent of poisoning. Thus, elucidated the cause of food poisoning has been unexplained for more than a decade. 3-Nitropropionic acid (BNPA) is a toxic substance produced by certain higher plants and fungi. As early as 1920, Gorter extracted a glucoside, the hiptagin, from the bark of the Hiptage mandablota Gaertn and hydrolyzed to give an acid called hiptagenic acid ). In 1949, Carter and other evidence of this substance is BNPA. And later one after another from a variety of higher plants and fungi metabolites isolated. For more than 60 years, foreign scientists on the BNPA management