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目的：分析甲状腺乳头状及滤泡状癌的疗效及相关因素。方法：1987年9月至1995年6月我院收治甲状腺乳头状及滤泡状癌患者76例，均行手术治疗，其中行术后放疗20例、术后化疗5例。结果：年龄＜40及≥40病例的5、8年生存率分别为91．1％、91．1％及71．4％、462％，P＜0．05；Ⅰ－Ⅱ期和Ⅲ－Ⅳ期病例的5、8年生存率分别为83．6％、69．8％和64．6％、50．5％，P＜0．05。腺叶切除加放疗病例（术后残余癌6例）的局部复发率为6．3％（1／16）；腺叶切除后未放疗病例（术后残余癌1例）的局部复发率为38．1％（8／21），P＝0．06。结论：单因素分析示生存率与年龄及分期密切相关，但经Cox比例风险模型分析未能得出阳性结果;腺叶切除后行放疗对降低局部复发率可能有帮助。
Objective: To analyze the efficacy and related factors of thyroid papillary and follicular carcinoma. METHODS: From September 1987 to June 1995, 76 patients with thyroid papillary and follicular carcinoma were treated with surgery. Among them, 20 patients received postoperative radiotherapy and 5 patients received postoperative chemotherapy. Results: The 5-year and 8-year survival rates of cases <40 and ≥40 were 91.1%, 91.1% and 71.4%, respectively, 462%, P<0.05; Stage I-II and III-IV The 5-year and 8-year survival rates of the cases were 83.6%, 69.8%, 64.6%, and 50.5%, respectively, P<0.05. The local recurrence rate was 6.3% (1/16) in cases of lobectomy and radiotherapy (6 cases with residual cancer after surgery); the rate of local recurrence was 38 cases with no radiation therapy after lobectomy (1 case with residual cancer). .1% (8/21), P=0.06. CONCLUSIONS: Univariate analysis showed that survival was closely related to age and stage, but the positive results could not be obtained by analysis of Cox proportional hazards model; radiotherapy after lobectomy may help reduce the local recurrence rate.