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目的 探索毒鼠强中毒的诊断及解救方法。方法 通过检测中毒患者外周血象、肝、肾功能、心肌酶谱、心电图、脑电图及部分患者血、尿或胃内容物毒物鉴定等 ,并应用安定、苯巴比妥钠、vitB6、二巯基丙磺酸钠、丙戊酸钠、血液灌流等方法解救 98例中毒患者疗效总结 ,同时与既往常规治疗的 2 0例患者进行比较。结果 全部病例均有神经系统损害、外周血白细胞、中性粒细胞、肝功、心肌酶增高 ,血检浓度与受损脏器、范围、严重程度呈正相关。治疗组获得较满意疗效 ,预后良好 ,而对照组 2 0例死亡 4例。结论 毒鼠强中毒者血检浓度越高 ,受损组织越多 ,临床症状越重 ,但只要及时地给予综合处理 ,重视各脏器的保护 ,重度中毒者亦能获得痊愈。
Objective To explore the diagnosis and rescue methods of tetramine poisoning. Methods The peripheral blood, liver and kidney function, myocardial zymogram, electrocardiogram, electroencephalogram and the blood, urine or stomach contents were identified in patients with poisoning. The patients were treated with diazepam, phenobarbital sodium, vitB6, dimercapto Propanesulfonic acid sodium, sodium valproate, hemoperfusion and other methods to rescue 98 cases of poisoning patients summary of efficacy, while conventional treatment with 20 patients were compared. Results All patients had neurological damage, peripheral blood leukocytes, neutrophils, liver function, myocardial enzymes increased, serum concentration and the affected organs, range, severity was positively correlated. The treatment group was more satisfied with the efficacy of a good prognosis, while the control group of 20 patients died in 4 cases. Conclusion The concentration of blood poisoning in tetramine poisoning group is higher, and the more damaged tissue, the more severe the clinical symptoms. However, as long as the integrated treatment is given in time, attention should be paid to the protection of each organ, and severe poisoning can be cured.