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目的了解咸阳市1~7岁(不含7岁)健康儿童脊髓灰质炎(脊灰)、麻疹、乙型脑炎(乙脑)及流行性脑脊髓膜炎(流脑)免疫水平状况,评价预防接种效果。方法采用酶联免疫吸附试验(ELISA)检测1~7岁健康儿童血清中脊灰、麻疹、乙脑及流脑IgG抗体,分析保护率。结果咸阳市脊灰、麻疹、乙脑及流脑IgG抗体阳性率分别为94.65%、95.67%、94.01%、89.94%;4种抗体保护水平均基本达到了85%以上;乙脑抗体阳性率以乾县(83.61%)和武功县(85.00%)为最低,流脑抗体阳性率以武功县(70.00%)和旬邑县(85.00%)为最低,差异有统计学意义(P<0.05)。结论咸阳市1~7岁健康儿童针对脊灰、麻疹、乙脑、流脑的抗体水平达到保护率,但应继续加强相关抗体水平监测工作,巩固计免工作成效。
Objective To investigate the status of polio (polio), measles, Japanese encephalitis (J) and epidemic cerebrospinal meningitis (IM) in healthy children aged from 1 to 7 years (excluding 7 years old) in Xianyang City, Vaccination effect. Methods Serum poliomyelitis, measles, encephalitis and meningitis IgG antibodies in healthy children aged 1 to 7 were detected by enzyme linked immunosorbent assay (ELISA), and the protection rate was analyzed. Results The positive rates of poliovirus, measles, encephalitis and meningitis IgG in Xianyang were 94.65%, 95.67%, 94.01% and 89.94%, respectively. The protective levels of four antibodies reached more than 85% Ganqian County (83.61%) and Wugong County (85.00%) were the lowest. The positive rates of meningococcal antibody were lowest in Wugong County (70.00%) and Xunyi County (85.00%), with statistical significance (P <0.05). Conclusion The antibody levels of polio, measles, Japanese encephalitis, and meningitis in healthy children aged 1 ~ 7 years in Xianyang reach the protection rate. However, monitoring of related antibody levels should be continued to consolidate the results of toll-free.