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随着人工晶状体设计技术不断发展以及新一代老龄化人群对生活质量要求的不断提高，白内障超声乳化联合人工晶状体植入术后能达到更好的全程视力和更高的视觉质量是白内障手术医师和患者的共同期望。非对称区域折射型多焦点人工晶状体（MIOLs）在提供远、中、近视力的同时减少不良光学现象的发生，满足了患者生活、工作的需求。现笔者就非对称区域折射型MIOLs的设计、临床效果以及体外实验的研究进展进行综述。“,”With the continuous development of intraocular lens design technology and the continuous improvement of quality of life for a new generation of aging population, cataract phacoemulsification combined with intraocular lens implantation can achieve better overall vision and higher visual quality. This is the common expectation of the cataract surgeon and the patient. Rotationally asymmetric multifocal intraocular lenses (MIOLs) reduce the incidence of adverse optical phenomena while providing distance, intermediate and near vision, meeting the needs of patients' lives and work. In this paper, the design, clinical effects and research progress of in vitro experiments on rotationally asymmetric MIOLs are reviewed.