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目的:观察美托洛尔治疗慢性充血性心力衰竭的临床疗效。方法治疗组60例慢性充血性心力衰竭患者在常规治疗基础上加服美托洛尔,初始剂量为6.25mgBidpo;对照组60例慢性充血性心力衰竭患者单用常规治疗;疗程为4周。心功能改善Ⅱ级或以上为显效;心功能改善Ⅰ级为有效;无变化或恶化为无效。结果治疗组显效41例(显效率68.9%),有效11例,总有效率88%,无效8例占(12%);对照组显效24例(显效率40%),有效18例,总有效率70%:无效18例占30%。两组比较总有效率有差异显著(P<0.05)。结论治疗慢性充血性心力衰竭,加用美托洛尔能显著提高临床疗效。
Objective: To observe the clinical efficacy of metoprolol in the treatment of chronic congestive heart failure. Methods Sixty patients with chronic congestive heart failure were treated with metoprolol on the basis of conventional treatment. The initial dose was 6.25 mg Bidpo. The control group of 60 patients with chronic congestive heart failure were treated with conventional therapy only for 4 weeks. Cardiac function improvement grade II or above is markedly effective; Grade 1 heart function improvement is effective; no change or worsening is ineffective. Results In the treatment group, 41 cases were markedly effective (effective rate was 68.9%), 11 were effective, the total effective rate was 88%, 8 cases were ineffective (12%); the control group was markedly effective in 24 cases (markedly effective rate 40%), effective 18 cases Efficiency 70%: invalid 18 cases accounted for 30%. The total effective rate was significantly different between the two groups (P <0.05). Conclusion Treatment of chronic congestive heart failure, with metoprolol can significantly improve the clinical efficacy.