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钙在心脏活动中的作用近年的生理学及药理学研究表明:钙无论在平滑肌、骨骼肌抑或心肌的收缩活动中,都起着重要作用。从分子水平看,骨骼肌的收缩,是肌细胞内收缩蛋白系统活化的结果。构成该系统的两种主要蛋白质,是肌凝蛋白和肌纤蛋白。两者以部分重叠的肌丝方式纵行排列。肌凝蛋白上有一“接合桥”,肌纤蛋白上有一“受桥点”。肌肉松弛时,接合桥与受桥点之间是相互分开的,且被原肌凝蛋白及原宁蛋白所阻隔;肌肉收缩时,阻隔被除去,肌纤蛋白丝向肌凝蛋白丝方向滑行,接合桥与受桥点强力结合,形成
The Role of Calcium in Cardiac Activity In recent years, physiological and pharmacological studies have shown that calcium plays an important role in the contraction of smooth muscle, skeletal muscle or cardiac muscle. At the molecular level, the contraction of skeletal muscle is the result of the activation of the contractile protein system in the muscle cells. The two major proteins that make up the system are myosin and myofibrillar. The two are partially overlapping myofilament longitudinal arrangement. Myosin has a “junction bridge”, there is a muscle fiber “by the bridge point.” Muscle relaxation, the junction bridge and bridge points are separated from each other, and the original myosin and the original ningling protein barrier; muscle contraction, the barrier is removed, myofibril filaments glide to the myofibril direction, Junction bridge and the strong point by the bridge to form