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小强荧光(SIF)细胞是指交感神经节内体积小、荧光强的颗粒细胞。近年来,不少学者用各种技术,如电镜、荧光组化、生化、电生理及药理学等,从不同角度对 SIF 细胞进行了多方面研究。现主要就 SIF 细胞的某些组织化学及生理作用概述如下。SIF 细胞这一概念,最早由 Er(?)nk(?)和 H(?)rk(?)nen 提出。当时,他们用甲醛诱发荧光方法,在显示大鼠颈上神经节内儿茶酚胺(CA)研究过程中,发现为特亮的黄色荧光性小细胞,故称为 SIF 细胞。随后有人报道,SIF 细胞不仅存于大鼠颈上神经节内,而且也出现在其它交感神经节以及其它种属动物的交感神经节内。但是,以后在文献记载上,对 SIF 细胞的定义比较混乱。有人根据肾上腺髓质内含去甲肾上腺素(NE)的嗜铬细胞也显出较强的甲醛诱发荧光,而且在人、兔、猫和狗的腹腔神经节内确实观察到有嗜铬反应的阳性细胞,
Small strong fluorescence (SIF) cells refer to small, highly fluorescent granulosa cells in the sympathetic ganglia. In recent years, many scholars have used various technologies, such as electron microscopy, fluorescence imaging, biochemistry, electrophysiology and pharmacology, to study SIF cells from various aspects. Some of the major histochemical and physiological roles of SIF cells are summarized below. The concept of SIF cells was first proposed by Er (?) Nk (?) And H (?) Rk (?) Nen. At that time, they used formaldehyde-induced fluorescence method, found in the rat superior cervical ganglion catecholamine (CA) during the study, was found to be bright yellow fluorescent small cells, it is called SIF cells. It was subsequently reported that SIF cells are not only found in the rat’s superior cervical ganglion, but also in other sympathetic ganglia and sympathetic ganglia of other species. However, the definition of SIF cells is confusing later in the literature. Some people also showed stronger formaldehyde-induced fluorescence based on the presence of norepinephrine (NE) -chromatically-chromaffin cells in the adrenal medulla, but no pheochromo-reaction was observed in the celiac ganglion of humans, rabbits, cats and dogs Positive cells,