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内淋巴囊和内淋巴管与内耳内淋巴引流有关,通过离子交换使内淋巴囊内的内淋巴液趋于一种低钾高钠状态。与水吸收有关的酶有钠-钾ATP酶和碳酸酐酶。在内淋巴囊的组织学中可见这些酶,可能与各种类型的细胞生理过程有关,以此调节内淋巴管和内淋巴囊系统的离子和液体浓度。阻断碳酸酐酶的作用可能控制梅尼埃病的症状。乙酰唑胺就可以减轻豚鼠实验性内淋巴囊水肿的程度。现经研究表明,乙酰唑胺作为一种特殊的碳酸酐酶抑制剂在鼠内淋巴囊进行活体研究,可用以阐明药物影响上皮细胞形态及呼吸作用的机理和程度。注射乙酰唑胺后的即刻,内淋巴囊上皮并无变化,亮上皮细胞与暗上皮细胞均可见许多扩张
Endolymphatic sac and endolymphatic vessels and lymphatic drainage of the inner ear, the endolymphatic sac within the endolymph by ion exchange tends to a low potassium and sodium status. Water absorption related enzymes are sodium - potassium ATPase and carbonic anhydrase. These enzymes, seen in the histology of the endolymphatic sac, may be involved in various types of cellular physiology to regulate the ionic and fluid concentrations in the endolymphatic vessels and the endolymphatic sac system. Blocking the action of carbonic anhydrase may control the symptoms of Meniere’s disease. Acetazolamide can reduce the degree of guinea pig experimental endolymphatic sac edema. Now studies have shown that acetazolamide as a special carbonic anhydrase inhibitor in vivo lymphatic sac in vivo studies can be used to clarify the drug affect the epithelial cell morphology and respiration mechanism and extent. Immediately after acetazolamide injection, there was no change in the endolymphatic sac epithelium, and many dilations were observed in both bright epithelial cells and dark epithelial cells