论文部分内容阅读
目的探索三峡库区淹没区兴山段肾综合征出血热(HFRS)人间和宿主动物间汉坦病毒携带状况的动态变化。方法采用描述流行病学、现场调查、实验室病原学、血清学监测方法。结果三峡库区兴山段自1997-2007年与三峡工程同步进行了HFRS监测,检测健康人群血清1831份,发现HFRS隐性感染率为2.18%,年龄以30～50岁人群为主,感染率为3.10%;职业以农民为主,感染率为3.23%;男女性别之比为0.74∶1。宿主动物监测捕获啮齿动物共741只,捕获率为2.19%,汉坦病毒(HV)平均带毒率为2.70%,监测点居民区室内鼠带毒率为2.79%;野外鼠带毒率为2.46%。室内鼠种以褐家鼠为优势鼠种,带毒率为3.58%;野外以黑线姬鼠为优势鼠种,带病毒率为4.41%。结论三峡库区是HFRS的潜在流行区,应采取相应预防控制措施。同时应加强库区HFRS的预警监测。
Objective To explore the dynamic changes of hantavirus carrying status between human and host animals in the Hemorrhagic fever with Renal Syndrome (HFRS) in the Xingshan Section of the Three Gorges Reservoir Area. Methods Describe epidemiology, field surveys, laboratory etiologies, serological surveillance methods. Results The HFRS monitoring was conducted in Xingshan section of the Three Gorges Reservoir Region from 1997 to 2007 along with the Three Gorges Project. The detection of 1831 serum samples from healthy population showed that the latent infection rate of HFRS was 2.18%, and the age was mainly from 30 to 50 years old. The infection rate 3.10%; occupations mainly farmers, the infection rate was 3.23%; gender ratio of 0.74:1. There were 741 rodents in the host animal surveillance and capture rate was 2.19%, the average rate of Hantavirus (HV) was 2.70%, the rate of indoor poisoning was 2.79% in the residential area of monitoring sites and 2.46 %. Rattus norvegicus was the dominant species in indoor rats, with the rate of 3.58%. In the wild, Apodemus agrarius was the dominant species with the virus rate of 4.41%. Conclusion The Three Gorges Reservoir Area is a potential epidemic area of HFRS. Corresponding prevention and control measures should be taken. At the same time, HFRS early warning and monitoring in reservoir area should be strengthened.