Barrett食管浅表癌行内镜下周围黏膜切除术后的鳞状上皮细胞再生

• 作 者: Satodate H. Inoue H. 杨瑗
• 机 构: Digestive Disease Cent er, Showa University, Northern Yokohama Hospital, 35-1 Chigasaki-chuo, Tsuzuk
• 出 处: 世界核心医学期刊文摘(胃肠病学分册)
• 发表日期: 2005年02期
• 关键词: 鳞状上皮细胞 黏膜切除术 食管 内镜 食管切除 抑酸治疗 表皮细胞再生 质子泵抑制剂 镜下切除 腺癌

Recent reports on the results of endoscopic ablation of Barrett’s mucosa have been promising, particularly when total mucosal ablation is coupled with aggres sive acid-suppression treatment using high-dose proton-pump inhibitor therapy . There is also a considerable literature on reepithelialization after ablative treatments in Barrett’s esophagus. This report describes a case of multifocal s uperficial adenocarcinoma arising in Barrett’s mucosa that was successfully tre ated with total circumferential endoscopic mucosal resection, with a subsequent follow-up of more than 2 years. This is the first report describing the process of squamous reepithelialization after endoscopic mucosal resection in Barrett’ s esophagus.

Recent reports on the results of endoscopic ablation of Barrett’s mucosa have been promising, particularly when total mucosal ablation is coupled with aggres sive acid-suppression treatment using high-dose proton-pump inhibitor therapy. There is also a considerable literature on reepithelialization after ablative treatments in Barrett’s esophagus. This report describes a case of multifocal s uperficial adenocarcinoma arising in Barrett’s mucosa that was successfully treted with total circumferential endoscopic mucosal resection, with a subsequent follow-up of more than 2 years. This is the first report describing the process of squamous reepithelialization after endoscopic mucosal resection in Barrett’s esophagus.