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目的探讨快速康复理念在腹腔远端胃癌根治术中的临床应用。方法选取2013年11月—2016年11月于漯河市中心医院行腹腔远端胃癌根治术的患者100例为研究对象,随机将其分为观察组(n=50)和对照组(n=50),对照组在腹腔远端胃癌根治术中应用常规治疗方式,观察组在腹腔远端胃癌根治术中应用快速康复理念,比较两组患者术后排气时间、术后疼痛评分(VAS评分)、住院时间、治疗费用、炎症因子水平[(白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)、超敏C-反应蛋白(hs-CRP)]和术后不良反应发生情况。结果观察组术后排气时间、术后疼痛评分、住院时间和治疗费用均显著优于对照组(P<0.05);观察组术后IL-6、IL-8、TNF-α和hs-CRP炎症因子水平均显著低于对照组,差异具有统计学意义(P<0.05);观察组术后并发症发生率为8.0%,显著低于对照组,差异具有统计学意义(P<0.05)。结论腹腔远端胃癌根治术中应用快速康复理念能显著促进患者术后恢复,减轻治疗费用和术后并发症产生风险,值得在临床上广泛推广。
Objective To investigate the clinical application of rapid rehabilitation concept in radical surgery for distal abdominal cancer. Methods A total of 100 patients with peritoneal distal gastric cancer underwent radical resection in the Central Hospital of Luohe between November 2013 and November 2016 were randomly divided into observation group (n = 50) and control group (n = 50) ). The control group received routine treatment in radical surgery of distal abdominal gastrectomy. The observation group applied the concept of rapid rehabilitation in the radical gastrectomy of distal abdominal gastrectomy. The postoperative exhaust time, postoperative pain score (VAS score) , Duration of hospitalization, cost of treatment, levels of inflammatory cytokines [IL-6, TNF-α, high-sensitivity C-reactive (Hs-CRP)] and postoperative adverse reactions were observed.Results The postoperative exhaust time, postoperative pain score, hospitalization time and treatment cost in the observation group were significantly better than those in the control group (P <0.05) The levels of IL-6, IL-8, TNF-α and hs-CRP in inflammatory cells were significantly lower than those in control group (P <0.05). The incidence of postoperative complications in observation group was 8.0% In the control group, the difference was statistically significant (P0.05) .Conclusion Applying the concept of rapid rehabilitation in the radical operation of distal abdominal gastric cancer can significantly promote the Postoperative recovery, reduce treatment costs and the risk of postoperative complications, should be popularized in clinical practice.