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目的:评价在人工流产术后口服短效避孕药优思明及单纯雌激素补佳乐对减少术后阴道流血时间、促进术后子宫内膜恢复、缩短首次月经恢复时间及减少术后并发症的临床疗效。方法:选择来我院因非意愿妊娠者要求行无痛人工流产者为研究对象,随机分为对照组即未用药组(n=200),优思明组(n=100)和补佳乐组(n=100)。3组均于术后2周及月经转归后1个月、3个月后随诊。观察术后阴道流血时间、术后2周子宫内膜厚度、首次月经恢复时间及术后3个月内并发症的发生情况。结果:①优思明组术后阴道流血时间短于对照组和补佳乐组,差异均有统计学意义(P<0.05);②优思明组术后2周子宫内膜略厚于对照组,但差异无统计学意义(P>0.05),补佳乐组术后2周子宫内膜厚度大于对照组和优思明组,差异有统计学意义(P<0.05)。③优思明组术后首次月经恢复时间短于对照组和补佳乐组,差异有统计学意义(P<0.05)。④用药组(优思明组和补佳乐组)术后并发症发生率均低于对照组,差异有统计学意义(P<0.05);用药组宫腔积液发生率低于对照组,差异有统计学意义(P<0.05)。结论:人工流产术后立即服用单纯雌激素对子宫内膜厚度的恢复优于避孕药,术后并发症的发生率更低。
OBJECTIVE: To evaluate the effect of oral administration of short-acting contraceptives yasumin and estrogen-only Jiale on the reduction of postoperative vaginal bleeding, postoperative recovery of endometrium, shortening the time of first menstruation and reduction of postoperative complications The clinical efficacy. Methods: Patients who had painless induced abortion in our hospital due to unwilling pregnancy were randomly divided into control group (n = 200), yusmin group (n = 100) and nociceptin Group (n = 100). Three groups were followed up for 2 weeks and 1 month after menstruation, 3 months later. Postoperative vaginal bleeding time, postoperative 2 weeks of endometrial thickness, first menstruation recovery time and postoperative complications within 3 months. Results: ① The vaginal bleeding time of YS group was shorter than that of control group and norepinephrine group (P <0.05); ② YS group was slightly thicker than control group 2 weeks after operation Group, but the difference was not statistically significant (P> 0.05). The thickness of endometrium of the two groups was significantly higher than that of the control group and the Yasmin group (P <0.05). ③ The first menstrual recovery time of Yasmin group was shorter than that of the control group and the nociceptin group, the difference was statistically significant (P <0.05). ④ The incidence of postoperative complications in the medication group (You Siming group and Bu Jiale group) were lower than those in the control group (P <0.05); the incidence of uterine fluid in the medication group was lower than that in the control group The difference was statistically significant (P <0.05). Conclusions: The recovery of endometrial thickness is superior to contraceptives when estrogen is taken immediately after abortion, and the incidence of postoperative complications is lower.