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目的设计一种新型动态力加载装置,研究力对镍铬烤瓷合金中镍离子释放的影响。方法依据人咀嚼的平均力(45 N)和频率(80次/min)设计一种动态力加载装置。运用该装置研究3种常用镍铬烤瓷合金(上齿牌、Stellite、BEGO)分别在pH 2.3和pH 7.0的人工唾液中镍离子的释放量。结果新型动态力加载装置能够模拟咀嚼频率进行人体平均力的加载。当pH 2.3时,上齿牌、Stellite和BEGO 3种镍铬烤瓷合金镍离子释放量分别为6.9(2.07)μg/cm2、3.7(0.662)μg/cm2和5.88(1.57)μg/cm2;当pH 7.0时,分别为0.272(0.059)μg/cm2、0.144(0.014)μg/cm2和0.435(0.053)μg/cm2。同种镍铬烤瓷合金材料在pH 2.3的人工唾液中镍离子的释放量均远大于在pH 7.0环境下的释放量,两者具有显著的统计学差异(P<0.01)。结论动态力加载装置可有效地被用于体外研究力对镍离子释放的影响。酸性环境可明显加快镍铬烤瓷合金中镍离子释放。本研究中Stellite镍铬烤瓷合金释放的镍离子量相对最少。
Objective To design a new type of dynamic force device to study the effect of force on nickel ion release in Ni-Cr porcelain alloys. Methods A dynamic force loading device was designed based on the average force of chewing (45 N) and frequency (80 beats / min). The device was used to study the release of Ni (superscript 3 +) from three kinds of commonly used Ni-Cr alloy (Stellite, BEGO) in artificial saliva at pH 2.3 and pH 7.0 respectively. Results The new dynamic force loading device was able to simulate the mastication frequency for loading the average body force. At pH 2.3, nickel ion release of the three Ni-Cr porcelain alloys from Shangtu brand, Stellite and BEGO were 6.9 (2.07) μg / cm2, 3.7 (0.662) μg / cm2 and 5.88 0.272 (0.059) μg / cm2, 0.144 (0.014) μg / cm2 and 0.435 (0.053) μg / cm2 at pH 7.0, respectively. The release of nickel ions in the artificial saliva of pH 2.3 with the same kind of Ni-Cr porcelain alloy material was much higher than that of the Ni-Cr alloy material with pH 7.0 release (P <0.01). Conclusion The dynamic force loading device can be effectively used to study the effect of force on nickel ion release in vitro. Acidic environment can significantly accelerate the nickel-chromium ceramic alloy nickel release. The amount of nickel ions released by Stellite Ni-Cr porcelain alloy is relatively low in this study.