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目的探讨戊酸雌二醇联合甲羟孕酮治疗人工流产不全的临床效果。方法选取2010年8月—2012年12月收治的人工流产不全患者68例,根据患者意愿分为研究组35例和对照组33例。研究组给予戊酸雌二醇2 mg/次+甲羟孕酮2 mg/次口服,2次/d。对照组给予新生化颗粒1袋/次冲服,2次/d。两组均治疗10 d观察宫腔内容物排出情况及疗效。计量资料采用t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果 B超回声异常率、有效率研究组分别为11.4%、88.6%,对照组分别为30.3%、69.7%,比较差异均有统计学意义(均P<0.05)。结论戊酸雌二醇联合甲羟孕酮治疗人工流产不全,可达到较为满意的清宫效果,值得在临床推广应用。
Objective To investigate the clinical effect of estradiol valerate combined with medroxyprogesterone in the treatment of artificial abortion. Methods Sixty-eight cases of induced abortion patients who were admitted from August 2010 to December 2012 were selected and divided into study group (35 cases) and control group (33 cases) according to patients’ wishes. Study group was given estradiol valerate 2 mg / times + medroxyprogesterone 2 mg / times orally, 2 times / d. The control group given new biochemical particles 1 bag / sub-blunt, 2 times / d. Both groups were treated for 10 days to observe the discharge of intrauterine contents and efficacy. Measurement data using t test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results The rates of abnormal ultrasound and effective rate of B ultrasound were 11.4% and 88.6% in the study group and 30.3% and 69.7% in the control group, respectively (all P <0.05). Conclusions Estradiol valerate combined with medroxyprogesterone in the treatment of induced abortion is not satisfactory, which can achieve a satisfactory result of curettage and is worthy of clinical application.