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从1981年2月至1986年7月,实行了91例择期结肠直肠手术。按肠道准备将91例分成三组:灭滴灵、新霉素组(45例),灭滴灵0.4g每日三次口服,连服三天,新霉素1.0g每日三次口服,连服三天;新霉素组(23例),新霉素1.0g每天三次口服,连服三天;链霉素组(24例),链霉素1.0g每日二次口服,连服三天。各组手术后切口感染率依次为10.91％28.31％、51.52％(P<0.05)。很明显,灭滴灵、新霉素予防结肠直肠术后切口感染比新霉素或链霉素更有效。
From February 1981 to July 1986, 91 patients undergoing elective colorectal surgery. According to intestinal preparation, 91 cases were divided into three groups: metronidazole, neomycin group (45 cases), metronidazole 0.4g three times daily orally, even for three days, neomycin 1.0g orally three times daily, even Serving three days; neomycin group (23 cases), neomycin 1.0g orally three times daily for three consecutive days; streptomycin group (24 cases), streptomycin 1.0g twice daily orally, and even served three day. Incision infection rates in each group were 10.91% 28.31%, 51.52% (P <0.05). Obviously, metronidazole, neomycin anti-colorectal incision infection than neomycin or streptomycin more effective.