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目的 了解围产期缺氧对新生儿肺动脉压的影响及其与临床的关系。方法 对有围产期缺氧史的新生儿行超声心动图检查 ,测定肺血流参数 :RPEP、RVET、AT,计算 RPEP/RVET,RPEP/AT及 PAMP,比较不同程度缺氧时肺动脉压的变化 ,肺动脉压升高与临床的关系。结果 重度缺氧组 RPEP/RVET、RPEP/AT、PAMP明显高于轻度缺氧组 ,而 AT明显低于轻度缺氧组 ;临床有明显呼吸困难 ,酸中毒 ,吸氧所需时间 >3天者其肺动脉压升高的发生明显高于无上述表现者。结论 围产期缺氧可引起肺动脉压升高 ,而且缺氧越重 ,升高越明显 ;临床有不能用原发病解释的缺氧或酸中毒较重时 ,应注重肺动脉压力的变化 ,并及早给予适当治疗
Objective To investigate the effect of perinatal hypoxia on pulmonary arterial pressure in neonates and its relationship with clinic. Methods Echocardiography was performed on infants with a history of hypoxia during perinatal period. Pulmonary blood flow parameters (RPEP, RVET, AT), RPEP / RVET, RPEP / AT and PAMP were calculated. Pulmonary arterial pressure Changes, pulmonary hypertension and clinical relationship. Results The levels of RPEP / RVET, RPEP / AT, PAMP in severe hypoxia group were significantly higher than those in mild hypoxia group and AT group was significantly lower than those in mild hypoxia group. The clinical manifestations of dyspnea, acidosis and oxygen were> 3 The incidence of pulmonary hypertension was significantly higher than those without these performance. Conclusion Perinatal hypoxia can cause pulmonary hypertension, and hypoxia increased, the more obvious increase; clinical can not be used to explain the primary disease of hypoxia or acidosis should pay attention to changes in pulmonary artery pressure, and Give appropriate treatment as soon as possible