Anti-oxidative Activity of Flavonoids from Cherry Leaves in Vitro

• 作 者: Shan ZHENG Feng ZHAO Zucheng LI Yuanfang WANG
• 机 构: Binzhou Medical University,Yantai Affiliated Hospital of Binzhou Medical University,
• 出 处: Medicinal Plant
• 发表日期: 2014年05期
• 关键词: flavonoids oxidative scavenging peroxidation inhibiting ferrous inhibit erythroc

[Objective] This study was undertaken to extract flavonoids from cherry leaves and to investigate the anti-oxidative activity in vitro. [Methods]The scavenging action on OH·and O-2·and its inhibiting effect on oxidative hemolysis of erythrocyte induced by H2O2and lipid peroxidation of hepatic tissue in mice were investigated in vitro. [Results] The flavonoids showed concentration-dependent scavenging effect on OH·and O-2·. The flavonoids also showed remarkable inhibiting effects on oxidative hemolysis of erythrocyte in mice induced by H2O2. When the final concentration of the flavonoids reached 30%,the inhibition rate was 74. 13%. It could inhibit lipid peroxidation of hepatic tissue in mice induced by vitamin C with low concentration and ferrous sulfate. And the inhibiting effect was concentration-dependent.When the final concentration of the flavonoids reached 30%,the inhibition rate was 68. 33%. [Conclusions]The total flavonoids from cherry leaf have concentration-dependent antioxidant activity in vitro.

[Objective] This study was undertaken to extract flavonoids from cherry leaves and to investigate the anti-oxidative activity in vitro. [Methods] The scavenging action on OH · and O-2 · and its inhibiting effect on oxidative hemolysis of erythrocyte induced by H2O2and lipid peroxidation of hepatic tissue in mice were investigated in vitro. [Results] The flavonoids showed concentration-dependent scavenging effect on OH · and O-2 ·. The flavonoids also demonstrated remarkable inhibiting effects on oxidative hemolysis of erythrocyte in mice induced by H2O2. When the final concentration of the flavonoids reached 30%, the inhibition rate was 74. 13%. It could inhibit lipid peroxidation of hepatic tissue in mice induced by vitamin C with low concentration and ferrous sulfate. And the inhibiting effect was concentration-dependent. When the final concentration of the flavonoids reached 30%, the inhibition rate was 68. 33%. [Conclusions] The total flavonoids from cherry leaf have concentration-dependent anti oxidant activity in vitro.