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目的了解中国北方健康女性青少年青春期性发育过程。方法采用横断面和纵向随访相结合的方法,对大庆市288名健康青少年女性进行为期4年的随访调查,观察身高、体重、体脂比例、第二性征、血清促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇水平的变化。结果大庆市青少年女性青春期性发育始动年龄为8.5岁±1.1岁,性发育始动时血清FSH、LH、雌二醇水平分别为0.2mIU/L、1.1mIU/L、0.06nmol/L(第95百分位数分别为2.5mIU/L、2.3mIU/L、0.12nmol/L)。月经初潮的年龄为12.4岁±1.2岁。乳房开始发育的平均年龄为8.5岁±1.6岁。结论中国北方青少年女性青春期性发育年龄有显著提前。
Objective To understand the adolescent sexual development of healthy female adolescents in northern China. Methods A total of 288 healthy adolescent females in Daqing City were followed up for 4 years. The height, weight, body fat percentage, secondary sexual characteristics, serum FSH, , Luteinizing hormone (LH), estradiol level changes. Results The onset age of adolescent sexual development in adolescent girls in Daqing was 8.5 ± 1.1 years. The serum levels of FSH, LH and estradiol at the beginning of sexual development were 0.2mIU / L, 1.1mIU / L and 0.06nmol / L, respectively 95 percentiles were 2.5mIU / L, 2.3mIU / L, 0.12nmol / L). The age of menarche is 12.4 ± 1.2 years old. The average age at which breast development begins is 8.5 years ± 1.6 years. Conclusion Adolescent sexual development age of adolescent girls in northern China is significantly advanced.