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目的:评价逍遥散临床抗抑郁效果的最佳剂量,为提高临床疗效提供实证。方法:采用临床随机双盲选取法,将门诊确诊的抑郁症患者60例随机分为逍遥散日用剂量370 g组30例,对照组30例,以逍遥散日用剂量320 g治疗,共治疗30天,以汉密尔顿抑郁量表(HAMD评定疗效。结果:逍遥散日用剂量370 g治疗组和日用剂量320 g对照组的总有效率分别为93.33%和56.67%,治疗组与对照组有显著性统计学差异。结论:中医临床治疗逍遥散最佳推荐日用剂量为370g。
Objective: To evaluate the optimal dose of Xiaoyaosan clinical antidepressant effect and provide evidence for improving clinical efficacy. Methods: Clinical randomized double-blind selection method, the outpatient diagnosis of depression in 60 patients were randomly divided into Xiaoyao San daily dose of 370 g group 30 cases, control group 30 cases, Xiaoyaosan daily dosage of 320 g treatment, a total of treatment 30 days, with Hamilton Depression Scale (HAMD evaluation efficacy.Results: Xiaoyao San Daily dosage of 370 g treatment group and daily dose of 320 g control group, the total effective rate was 93.33% and 56.67%, respectively, the treatment group and the control group Significant statistical difference.Conclusion: The best recommended daily dose of Xiaoyao San is 370g.