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目的探索囊性星形细胞肿瘤的外科治疗方法。方法通过立体定向32P瘤内放疗和手术切除囊性星形细胞肿瘤64例,其中手术切除37例,立体定向32P瘤内放疗27例;病理诊断星形细胞瘤24例,间变性星形细胞瘤26例,胶质母细胞瘤14例。结果临床和CT随访36~65个月,存活26例,死亡38例;经统计学处理,完全囊性星形细胞肿瘤行立体定向32P瘤内放疗2年和3年存活率、缓解时间及术后复发时间较手术切除有显著性差异,而部分囊性星形细胞肿瘤无显著性差异。结论完全囊性星形细胞肿瘤首选立体定向瘤内放疗,部分囊性星形细胞肿瘤按肿瘤位置确定手术方式。
Objective To explore the surgical treatment of cystic astrocytic tumors. Methods Stereotactic 32P intratumoral radiotherapy and surgery were performed to remove 64 cases of cystic astrocytic tumors. Among them, 37 cases underwent surgical resection and 27 cases underwent stereotactic 32P intratumoral radiotherapy. 24 cases of astrocytomas underwent pathological diagnosis and anaplastic astrocytoma. In 26 cases, there were 14 cases of glioblastoma. Results Clinical and CT follow-up 36-65 months, 26 cases survived, and 38 cases died. After statistical analysis, stereotactic 32P intratumoral radiotherapy for 2 years and 3 years survival rate, remission time and surgery were performed. The postoperative recurrence time was significantly different from the surgical resection, but there was no significant difference in some cystic astrocytic tumors. Conclusion Stereotactic intracranial radiotherapy is preferred for completely cystic astrocytic tumors, and partial cystic astrocytic tumors are determined according to the location of the tumor.