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目的观察注射用泮托拉唑治疗上消化道出血的临床效果及安全性。方法将79例上消化道出血患者随机分为治疗组40例和对照组39例,两组分别给予注射用泮托拉唑40mg和注射用雷尼替丁100mg静脉滴注,2次/d,疗程3天。观察两组临床症状改善情况、止血效果及不良反应。结果治疗组和对照组止血显效率分别为47%和26%,总有效率分别为95.5%和70%,治疗组的临床疗效明显优于对照组。结论注射用泮托拉唑治疗上消化道出血疗效肯定且不良反应少。
Objective To observe the clinical effect and safety of pantoprazole for upper gastrointestinal bleeding. Methods A total of 79 patients with upper gastrointestinal bleeding were randomly divided into treatment group (n = 40) and control group (n = 39). The two groups were given pantoprazole 40 mg and ranitidine 100 mg intravenously twice a day, Treatment for 3 days. The clinical symptom improvement, hemostatic effect and adverse reaction in both groups were observed. Results The effective rates of hemostasis in treatment group and control group were 47% and 26%, respectively. The total effective rates were 95.5% and 70% respectively. The clinical efficacy of the treatment group was significantly better than that of the control group. Conclusion Intravenous injection of pantoprazole in the treatment of upper gastrointestinal bleeding with positive and less adverse reactions.